Mesenchymal Stem Cells - Advances And Applications

 Published On: Aug, 2015 |    No of Pages: 171 |  Published By: BioInformant | Format: PDF
Request Free Sample

The purpose of this global strategic report is to prepare executives of stem cell product companies, stem cell therapy companies, and stem cell industry investors, with the knowledge necessary to make informed, educated decisions about opportunities for commercialization within the rapidly-evolving mesenchymal stem cell (MSC) marketplace.

It is produced for:
• Management of Stem Cell Product Companies
• Management of Stem Cell Therapy Companies
• Stem Cell Industry Investors

It is designed to increase efficiency and effectiveness in:
1. Commercializing MSC research products, technologies, and cell-based therapies
2. Making intelligent MSC investment decisions
3. Launching high-demand MSC products
4. Capitalizing on new and emerging MSC industry trends
5. Dominating market share within the MSC marketplace
6. Understanding your strengths and weaknesses relative to the competition

Because mesenchymal stem cell researchers represent a rapidly growing, well-funded research community, this report presents strategies that research supply companies can use to develop product lines that will be of high value to the research community. It also presents valuable content for cellular therapy companies, both quantifying and qualifying the market for MSC based therapeutics and related clinical applications. Thirdly, it is important for pharmaceutical companies to understand underlying market forces and to assess areas of MSC research progress as opportunities for drug and therapy development, including how advances in MSC research can reveal potential new drug targets, improve methods of drug delivery, and provide personalized treatment strategies.

As such, this global strategic report explores topics of interest to three types of industry participants: Research supply companies, cell therapy companies, and drug development companies.

Because it is vital to assess trends that are occurring within the MSC market, the report also considers a range of important trend data for the MSC market, including trend rate data for MSC clinical trials, patents, grants, scientific publications, and more. Additionally, it considers the driving force for mergers and acquisitions that are occurring within the MSC market. With 4 zettabytes (10^21st bytes) of data now in existence worldwide, this report eliminates superficial information and drill down to the key metrics that will provide executives and investors with the data required to make educated decisions that will drive revenue.
In addition, executives and investors must to have a clear understanding of opportunities and threats occurring within the MSC marketplace. As the technology surrounding MSC derivation and differentiation advances, new opportunities for scaling up the manufacture and distribution of MSC research products and cell-based therapies has emerged. As clinical trials investigating MSCs increase in number, more cell therapy companies are also exploring clinical applications of MSCs and becoming competitive threats within the marketplace. Other examples of emerging threats within the MSC industry include the potential for inconsistent or negative clinical findings, competing technologies, and fluctuating government stances on whether manipulation of stem cells prior to transplantation into humans should be allowed (a current “hot topic” among regulatory bodies within the U.S. and other regions). In the rapidly-evolving MSC marketplace, being fully informed about both opportunities and threats is an essential aspect of being able to survive and thrive.

For a decade or so, MSCs were largely perceived to be a supportive, feeder layer for hematopoietic stem cells (HSCs). Then, sentiment within the research community swung strongly in the opposite direction, with MSCs hastily labeled as “stem cells,” despite demonstrating a considerably limited differentiation potential. This characterization was misleading and drove research towards outcomes that involved semi-differentiated and often non-engrafting cells. Because MSC differentiation often does not explain the benefits of MSC treatment, the answer to how MSCs exert their effects is still being explored across the public, private, academic, and government sectors.

Indeed, the traditional view that mesenchymal stem cells heal by maturing into replacement cells for damaged tissue is either partially (or fully) untrue. Current research now suggests that the power of MSCs more likely comes from their ability to regulate the immune response and influence the human body’s own regenerative machinery. This understanding is critical to pursing effective avenues for the commercialization of MSC products, technologies, and therapies.

The content and statistics contained in this report were compiled using a broad range of sources, including:
• Stem Cell Grant Funding Database (RePORT Database, CIRM, MRC, Wellcome Trust - UK)
• Stem Cell Patent Database (United States Patent and Trade Office, World Intellectual Property Organization)
• Stem Cell Clinical Trial Database (ClinicalTrials.gov, International Clinical Trials Registry Platform, European Union Clinical Trials Register )
• Stem Cell Scientific Publication Database (PubMed, Highwire Press, Google Scholar)
• Stem Cell Product Launch Announcements (Trade Journals, Google News)
• Stem Cell Industry Events (Google News, Google Alerts)
• Stem Cell Company News (SEC Filings, Investor Publications, Historic Performance)
• International Surveys (Electronically Distributed End-User Surveys)
• And More

Key findings within this report include:

• Trend Rate Data for MSC Grants, Clinical Trials, and Scientific Publications
• Analysis of MSC Patent Environment, including Key Patents and Patent Trends
• Advances in MSC Research Applications
• Crucial Advances in MSC Therapy Development
• Research Priorities by Market Segment
• Geographical Assessment of MSC Innovation
• Competitive Environment Analysis
• Market Size Determinations
• Company Profiles for MSC Industry Leaders
• And Much More

In summary, the mesenchymal stem cell marketplace is composed of several sectors experiencing strong growth. Claim this global strategic report to become informed, to gain a strategic advantage over your competition, and most importantly, to take advantage of important MSC industry trends.

1. REPORT OVERVIEW 10
1.1 Statement of the Report 10
1.2 EXECUTIVE SUMMARY 12
2. INTRODUCTION 14
2.1 Regenerative Medicine (RM) and Advanced Therapies Industry: A Brief Overview 16
2.2 Global Breakdown of Major RM Industries by Region 17
2.3 Breakdown of Global RM Companies by Type 18
2.4 Number of Therapeutic Companies, Approved Products and Clinical Trials in RM Sector 18
2.5 Number of RM Clinical Trials by Phase of Development 19
2.6 Number of RM Companies by Disease Focus Area 20
2.7 Major Financial Events in RM Industry 21
2.8 Major Partnerships and Acquisitions in RM Industry 21
2.9 Total Financings in RM Industry by Segment 22
2.10 Type of Financing for RM Industry 23
2.11 Major Regulatory Milestones in RM Industry 23
2.12 Major Data and Technology Events in RM Industry 24
2.13 Major Pharma and Biotech Companies Active in Advanced Therapies 25
2.14 Major Corporate Partnerships in RM Industry 26
2.15 Anticipated Major RM Clinical Events 28
2.16 Notable Deals and Acquisitions in RM, Cell and Gene Therapy Space, 2013-2014 29
2.17 Big Pharma’s Perception of RM 30
2.18.1 Major Therapeutic Opportunities for Big Pharma in Cell Therapy and RM 31
2.18.1.1 Current Opportunities 31
2.18.1.2 Near-Term Opportunities 31
2.18.1.3 Long-Term Opportunities 32
3. CELL THERAPY INDUSTRY: A BRIEF OVERVIEW 33
3.1 Types of Stem Cells Used in Cell Therapy 33
3.1.1 Human Embryonic Stem Cells (hESCs) 33
3.1.2 Induced Pluripotent Stem Cells (iPSCS) 33
3.1.3 Hematopoietic Stem Cells (HSCs) 34
3.1.4 Mesenchymal Stem Cells (MSCs) 34
3.1.5 Adipose Stem Cells (ASCs) 34
3.1.6 Neural Stem Cells (NSCs) 34
3.2 Cell Therapy Product Candidates in Late-Stage Clinical Development 35
3.3 Cell Therapy Product Candidates in Early-Stage Clinical Development 36
3.4 Cell Therapy Products Being Developed for Cardiovascular Indication 38
3.5 Cell Therapy Products Being Developed for Central Nervous System Indication 40
3.6 Cell Therapy Products Developed and Being Developed for Wound Care 41
3.7 Cell Therapy Products Developed and Being Developed for Spine and Orthopedics 42
3.8 Cell Therapy Products Being Developed for Diabetes 45
3.9 Cell Therapy Products Being Developed for Autoimmune Diseases 45
3.10 Combination of Cell and Gene Therapy Products in Development 46
3.11 Cancer Programs Utilizing the Combination of Cell and Immunotherapy 47
3.12 Major Commercially Available Cell Therapy Products 49
3.13 Cell Therapy Products Approved in South Korea 51
3.14 Cell Therapy Clinical Trials: An Overview 52
3.14.1 Cell Therapy Clinical Trials by Geography 52
3.14.2 Top Eight Countries in Cell Therapy Clinical Trials 53
3.14.3 Major Cell Types in Cell Therapy Clinical Trials 54
3.14.4 Major Disease Indications Addresses by Cell Therapy Clinical Trials 54
3.15 Fifteen Major Cell Therapies in Phase III 55
3.15.1 Prochymal 55
3.15.2 Mesenchymal Precursor Cell (MPC) 56
3.15.3 MyoCell 56
3.15.4 Ixmyelocel-T 56
3.15.5 ELAD 57
3.15.6 HP802 57
3.15.7 StemEx (Carlecortemcel-L) 57
3.15.8 LaViv 57
3.15.9 GSK 2696273 58
3.15.10 Renew 58
3.15.11 NT-501 (Renexus) 58
3.15.12 Neocart 58
3.15.13 DeNovo ET 59
3.15.14 MACI 59
3.16 Clinical Trial Failures in Cell Therapy in 2014 59
3.16.1 Failure of Phase II for MultiStem 59
3.16.2 Failure of Cardio 133 Trial 59
3.16.3 Termination of AlloCure’s ACT-AKI Trial 60
3.16.4 Failed Stroke Trial in India 60
3.16.5 Failure of HeartiCellGram-AMI Trial 60
3.16.6 Failure of Adipose MSCs in ARDS 60
3.16.7 CD133+ in CLI Not Feasible 60
3.16.8 Failed MSC Trial for Multiple Sclerosis 60
3.16.9 Failure of Chinese Diabetes Trial 61
3.16.10 Failed Efficacy Trial in AMI by Stempeucel 61
3.17 A Sampling of Stem and Progenitor Cell-Based Trials with 2014 Clinical Readouts 61
3.18 Major Cell Therapy Companies and their Locations 62
3.19 Involvement of Multinational Companies (MNCs) in Cell Therapy Sector 67
4. MESENCHYMAL STEM CELLS (MSCs): AN OVERVIEW 69
4.1 Biological Properties of MSCs Contributing to their Therapeutic Effects 69
4.1.1 MSCs’ Capacity to Migrate and Engraft 69
4.1.2 MSCs’ Differentiation Potential 70
4.1.3 MSCs’ Potential to Secrete Multiple Bioactive Molecules 70
4.1.4 MSCs’ Potential for Immunomodulatory Functions 71
4.1.5 Variable Immunophenotype of MSCs 72
4.2 Factors Impacting MSCs Acquisition 73
4.3 Major Clinical Sources of MSCs 74
4.3.1 Bone Marrow-Derived Mesenchymal Stem Cells (BMMSCs) 74
4.3.1.1 BMMSCs and Kidney 75
4.3.1.2 BMMSCs and Pancreas 75
4.3.1.3 BMMSCs and Heart 76
4.3.1.4 BMMSCs and Liver 76
4.3.1.5 BMMSCs and Brain 77
4.3.1.6 BMMSCs and Intestine 77
4.3.1.7 BMMSCs and Bone 78
4.3.2 Adipose-Derived Mesenchymal Stem Cells 79
4.3.2.1 Selected ADSC Secretomes and their Functions 80
4.3.3 Mesenchymal Stem Cells (MSCs) Derived from Wharton’s Jelly 81
4.3.3.1 Clinical Application Properties of WJ-MSCs 81
4.3.3.2 Immunoprivileged Status of WJ-MSCs 81
4.3.3.3 Clinical Applications of WJ-MSCs 81
4.3.4 Umbilical Cord Blood-Derived MSCs (UCBMSCs) 83
4.4 Dominance of MSCs in Cell Therapy Clinical Trials 84
4.5 Major Diseases Addressed by MSCs in Current Clinical Trials 86
4.5.1 MSCs for Treating Liver Diseases 87
4.5.2 MSCs for Neurodegenerative Diseases 88
4.5.3 Clinical Trials Using MSCs for Autoimmune Diseases 88
4.5.4 Clinical Trials Using MSCs for Diabetes 89
4.5.5 MSCs for Cardiovascular Repair 90
4.5.6 MSCs for Musculoskeletal Diseases 90
4.5.6.1 Studies Using MSCs for Musculoskeletal Indications by Leading Countries 92
4.5.5.2 Application of MSCs in Joint Diseases 93
4.5.7 MSCs in Neuron/Spinal Cord Diseases 95
4.5.8 MSC Infusion for GvHD 96
4.5.9 MSCs for Crohn’s Disease 97
4.5.10 MSCs in Wound Healing 97
4.5.11 Increasing Focus on Immunological Properties of MSCs 99
4.5.12 Percentage of MSCs Clinical Trials by Different Phases 100
4.5.13 Selected MSCs Late-Stage Pipeline Cell Therapies 100
5. A BRIEF OVERVIEW OF THE MARKET FOR STEM CELLS 102
5.1 Global Market for Stem Cells by Disease Indication 105
6. SELECTED COMPANY PROFILES 107
6.1 American Type Culture Collection Inc. (ATCC) 107
6.2 Anterogen Co., Ltd. 108
6.2.1 Cupistem Injection 108
6.2.2 Queencell 108
6.3 Apceth GmbH & Co. KG 109
6.3.1 Apceth’s Research Areas 109
6.4 BioCardia Inc. 110
6.5 BioRestorative Therapies Inc. 111
6.5.1 brtxDISC 111
6.5.2 ThermoStem 111
6.6 Bone Therapeutics SA 112
6.6.1 PREOB 112
6.6.2 ALLOB 112
6.7 BrainStorm Cell Therapeutics Inc. 113
6.7.1 NurOwn 113
6.8 CellGenix Technologie Transfer GmbH 114
6.9 Celprogen Inc. 115
6.10 CellTherapies P/L 116
6.10.1 Services 116
6.10.2 Product 117
6.11 Cesca Therapeutics Inc. 117
6.11.1 Surgwerks 118
6.11.2 Cellwerks 118
6.11.3 AutoXress (AXP) 118
6.11.4 MarrowXpress (MXP) 118
6.11.5 Res-Q BMC 118
6.12 Cyagen Biosciences Inc. 119
6.12.1 Mesenchymal Stem Cells from Cyagen 119
6.12.2 Adipose-Derived Mesenchymal Stem Cells from Cyagen 120
6.12.3 Mesenchymal Stem Cells with GFP from Cyagen 120
6.12.4 Adipose-Derived Mesenchymal Cells with GFP from Cyagen 121
6.12.5 Stem Cell Culture Media from Cyagen 121
6.12.6 Stem Cell Differentiation Media from Cynagen 122
6.12.7 Primary Cells from Cynagen 122
6.12.8 Cyagen’s Cryopreservation Media 123
6.12.9 Cyagen’s Primary Cell Culture Media 124
6.12.10 General Cell Culture Supplements and Specialty Reagents from Cyagen 124
6.13 Cynata Therapeutics Ltd. 125
6.13.1 Cymerus Platform Technology 125
6.14 Cytori Therapeutics Inc. 126
6.14.1 Clinical Trial for Scleroderma 126
6.14.2 Clinical Trials for Osteoarthritis 126
6.15 Escape Therapeutics 127
6.16 Genlantis 128
6.17 Kite Pharma Inc. 129
6.17.1 Engineered Autologous Cell Therapy (eACT) 129
6.17.2 DC-Ad GM-CAIX 129
6.18 Life Technologies Corporation 130
6.19 Lonza Group Ltd. 131
6.19.1 Selected Products 131
6.20 Medipost Co. Ltd. 132
6.20.1 Cartistem 133
6.20.2 Neurostem 133
6.20.3 Pneumostem 133
6.21 Mesoblast Ltd. 134
6.21.1 Mesoblast’s Product Pipeline Overview 134
6.22 NuVasive Inc. 136
6.22.1 Osteocel 136
6.23 Octa Therapeutics Inc. 136
6.24 Organogenesis Inc. 137
6.24.1 Apligraf 137
6.24.2 Dermagraft 138
6.25 Orthofix International N.V. 138
6.25.1 Trinity Elite 138
6.25.2 Trinity Evolution 139
6.26 Osiris Therapeutics Inc. 139
6.26.1 Grafix 139
6.26.2 OvationOS 139
6.26.3 Cartiform 140
6.27 Pluristem Therapeutics Inc. 140
6.27.1 PLX Cells 140
6.28 PromoCell 141
6.29 Regeneus Ltd. 142
6.29.1 Products 142
6.30 ScienCell Research Laboratories 143
6.31 Stemcell Technologies Inc. 146
6.32 Stemedica Cell Technologies Inc. 149
6.32.1 Stemedyne MSC 149
6.32.2 Stemedyne NSC 149
6.32.3 Stemedyne RPE 149
6.33 Stempeutics Research Pvt. Ltd. 150
6.33.1 Stempeucel 150
6.33.2 Stempeutron 150
6.33.3 Stempeucare 151
6.34 TiGenix N.V. 151
6.34.1 Cx601 152
6.34.2 Cx611 152
6.34.3 Cx621 152
6.35 Vericel Corporation 153

INDEX OF FIGURES

FIGURE 3.1: Number of Cell Therapy Clinical Trials, 2011-2014 52
FIGURE 3.2: Cell Therapy Clinical Trials (%) by Geography in 2014 53
FIGURE 3.3: Top Eight Countries in Cell Therapy Clinical Trials (%) in 2014 53
FIGURE 3.4: Major Cell Types in Cell Therapy Clinical Trials (Numbers) in 2014 54
FIGURE 3.5: Major Cell Therapy Clinical Trials (Numbers) by Indication in 2014 55
FIGURE 4.1: Schematic of Factors Impacting MSC Acquisition 73
FIGURE 4.2: Number of Clinical Trials Using MSCs, 2004-2014 86
FIGURE 4.3: Increasing Focus on the Immunological Properties of MSCs 99
FIGURE 4.4: Percentage of MSCs Clinical Trials by Different Phases 100
FIGURE 5.1: Global Market for Stem Cells, Stem Cell Services, Cord Blood Banking, Stem Cell Therapies and Bone Marrow Transplants, Through 2021 104
FIGURE 5.2: Global Market for Stem Cells by Disease Indication, Through 2021 106

INDEX OF TABLES

TABLE 2.1: Global Breakdown of Major RM Industries by Region .….17
TABLE 2.2: Global Breakdown of RM Companies by Type, 2014….. 18
TABLE 2.3: Number of Therapeutic Companies, Approved Products and Clinical Trials, 2014…..19
TABLE 2.4: Number of RM Clinical Trials by Phase in 2014….....19
TABLE 2.5: Number of RM Companies by Disease Focus Area….…20
TABLE:2.6: Major Financial Events in RM Industry in 2014.21
TABLE 2.7: Major Partnerships and Acquisitions in RM Industry in 2014..22
TABLE 2.8: Total Financings in RM Industry by Segment in 2014.….22
TABLE 2.9: Type of Financing for RM Industry in 2013 and 2014…..23
TABLE 2.10: Major Regulatory Milestones in RM Industry in 2014…24
TABLE 2.11: Major Data and Technology Events in RM Industry in 201425
TABLE 2.12: Major Pharma and Biotech Companies Active in Advanced Therapies in 2014…..26
TABLE 2.13: Major Corporate Partnerships in RM Industry in 2014..27
TABLE 2.14: Anticipated Major RM Clinical Events in 2015…...28
TABLE 2.15: Notable Deals and Acquisitions in RM, Cell and Gene Therapy.29
TABLE 2.16: Big Pharma's Interest on Investing in RM by Sector….31
TABLE 2.17: Most Promising Areas in RM for Big Pharma.32
TABLE 3.1: Different Types of Stem Cells Used in Cell Therapy and their Characteristics...35
TABLE 3.2: Cell Therapy Product Candidates in Late-Stage Clinical Development36
TABLE 3.3: Cell Therapy Product Candidates in Early-Stage Clinical Development…..37
TABLE 3.4: Cell Therapy Products Being Developed for Cardiovascular Indication…...39
TABLE 3.5: Cell Therapy Products Being Developed for Central Nervous System.40
TABLE 3.6: Cell Therapy Products Developed and Being Developed for Wound Care..41
TABLE 3.7: Cell Therapy Products for Spine and Orthopedics...43
TABLE 3.8: Cell Therapy Products Being Developed for Diabetes…45
TABLE 3.9: Cell Therapy Products Being Developed for Autoimmune Diseases…46
TABLE 3.10: Combination of Cell and Gene Therapy Products in Development….47
TABLE 3.11: Cancer Programs Utilizing the Combination of Cell and Immunotherapy..48
TABLE 3.12: Major Commercially Available Cell Therapy Products..50
TABLE 3.13: Cell Therapy Products Approved in South Korea..51
TABLE 3.14: A Sampling of Stem and Progenitor Cell-Based Trials with 2014 Readouts….62
TABLE 3.15: Major Cell Therapy Companies in the World..63
TABLE 3.15: Major Cell Therapy Companies in the World (Continued)…64
TABLE 3.15: Major Cell Therapy Companies in the World (Continued)…65
TABLE 3.15: Major Cell Therapy Companies in the World (Continued)…66
TABLE 3.15: Major Cell Therapy Companies in the World (Continued)…67
TABLE 3.16: Major Companies and Products in Development in Cell Therapy Sector....67
TABLE 3.16: Major Companies and Products in Development in Cell Therapy (Continued…..…..68
TABLE 4.1: Origin and Cell Typed Derived from MSCs….....70
TABLE 4.2: Important Bioactive Molecules Secreted by MSCs and Their Functions…...71
TABLE 4.3: Immunomodulatory Effects of MSCs on Immune Cells....72
TABLE 4.4: Cell Surface Antigen Expressions of MSCs Isolaed from Different Sources..…..72
TABLE 4.5: Major Clinical Sources of MSCs...74
TABLE 4.6: A Sample of Clinical Trials Using BMMSCs for Kidney Diseases…...…75
TABLE 4.7: A Sample of Clinical Trials Using BMMSCs for Diabetes….....75
TABLE 4.8: A Sample of Clinical Trials Using BMMSCs for Heart Diseases…..…...76
TABLE 4.9: A Sample of Clinical Trials Using BMMSCs for Liver Diseases…..….…77
TABLE 4.10: Clinical and Experimental Therapies Using MSCs for Neural Diseases…..…....77
TABLE 4.11: A Sample of Clinical Trials Using MSCs for Intestinal Diseases...78
TABLE 4.12: A Sample of Clinical Trials Using BMMSCs for Musculoskeletal Diseases..…..78
TABLE 4.13: ADSCs Transplantation in Clinical Trials by Region in Phase III, 2014..….80
TABLE 4.14: Selected ADSC Secretomes and their Functions…..…..80
TABLE 4.15: A Summary of Clinical Trials Using WJ-MSCs.82
TABLE 4.15: A Summary of Clinical Trials Using WJ-MSCs (Continued)..83
TABLE 4.16: Clinical Trials Using UCBMSCs and Targeted Diseases..….84
TABLE 4.17: Dominance of MSCs in 2014 Stem Cells Clinical Trials.85
TABLE 4.18: Clinical Trials Using MSCs by Disease Type, 2014.…...87
TABLE 4.19: A Sample of Clinical Trials Using MSCs for Liver Diseases..87
TABLE 4.20: A Sample of Clinical Trials Using MSCs for Neurodegenerative Diseases….…88
TABLE 4.21: A Sample of Phase I and II Clinical Trials for Autoimmune Diseases….….89
TABLE 4.22: A Sample of Clinical Trials Using MSCs for Diabetes....89
TABLE 4.23: A Sample of Clinical Trials Using MSCs for Cardiovascular Diseases..…..90
TABLE 4.24: Clinical Trials Involving MSCs for Bone and Cartilage Repair…...91
TABLE 4.25: Studies Using MSCs for Musculoskeletal Indications by Countries in 2014…...92
TABLE 4.26: A Sample of Current Clinical Trials Using MSCs for Osteoarthritis..…93
TABLE 4.27: A Sample of Clinical Trials Involving MSCs for Bone and Cartilage Repair…..….….94
TABLE 4.28: Clinical Trials Using MSCs for Neuron and Spinal Cord Diseases...…95
TABLE 4.29: Clinical Experience of MSCs in GvHD Treatment…96
TABLE 4.30: A Sample of Clinical Trials Using MSCs for Crohn's Disease97
TABLE 4.31: Clinical Studies Using MSCs for Wound Healing…..…..98
TABLE 4.32: Selected MSCs Late-Stage Pipeline Therapies…...….101
TABLE 5.1: Global Market for Stem Cells, Through 2021….…..104
TABLE 5.2: Global Market for Stem Cells by Disease Indication, Through 2021.….…..106
TABLE 6.1: BioCardia's Product Pipeline Overview.…110
TABLE 6.2: Bone Therapeutics' Product Pipeline….….…...113
TABLE 6.3: Cyagen's Mesenchymal Cells…...….119
TABLE 6.4: Cyagen's Adipose-Derived MSCs…..120
TABLE 6.5: Cyagen's MSCs with GFP….…..120
TABLE 6.6: Cyagen's Adipose-Derived MSCs with GFP....121
TABLE 6.7: Cyagen's Stem Cell Culture Media....122
TABLE 6.8: Cyagen's Stem Cell Differentiation Media…....122
TABLE 6.9: Primary Cells from Cyagen..123
TABLE 6.10: Cyagen's Cryopreservation Media...123
TABLE 6.11: Cyagen's Primary Cell Culture Media..…124
TABLE 6.12: General Cell Culture Supplements and Specialty Reagents from Cyagen…..….....125
TABLE 6.13: Escape Therapeutics' Pipeline Products.…...127
TABLE 6.14: Kite Pharma's Pipeline and Clinical Trials…..130
TABLE 6.15: Mesoblast's Product Pipeline Overview….….135
TABLE 6.16: Octa's Pipeline of Therapeutic Programs…...135
TABLE 6.17: Regeneus' Product Pipeline..…143
TABLE 6.18: Stempeucel in Clinical Trials by Indication…..151
TABLE 6.19: Vericel Corporation's Product Portfolio.......…153
TABLE 6.20: Summary Table for the Companies and Their Product Types ...154


If the above report does not have the information suitable for your business, we can provide custom research that can be lucrative for your business or enhance your profession.