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Highlights -Comprehensive 1,125-page market segmentation analysis of the French NAT market. -Major issues pertaining to the French NAT laboratory practice, as well as key economic, regulatory, demographic, social and technological trends with significant market impact during the next five years. -An extensive review of DNA probe and biochip technologies, test formats, detection methodologies, trends in testing automation and amplification methods. -Five-year test volume and reagent sales forecasts for the following categories: - Infectious Diseases - Cancer - Forensic Testing - Genetic Diseases - Paternity Testing/HLA Typing -Review of testing methodologies and instrumentation technologies. -Feature comparison of automated and semiautomated analyzers. -Sales and market shares of leading suppliers. -Over 60 specific opportunities for NAT instruments, test systems, IT and auxiliary products. -Profiles of major suppliers, and emerging market entrants, including their sales, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies. -Alternative market penetration strategies. -Potential market entry barriers and risks. -Business planning issues and concerns.
I. Introduction II. Major Product Development Opportunities A. Instrumentation B. Reagent Kits and Test Systems/panels C. Computers, Software and Automation D. Auxiliary Products III. Design Criteria for Decentralized Testing Products IV. Alternative Market Penetration Strategies A. Internal Development B. Collaborative Arrangements C. University Contracts D. Distribution Strategies For Decentralized Testing Markets V. Potential Market Entry Barriers and Risks A. Market Maturity B. Cost Containment C. Competition D. Technological Edge And Limitations E. Patent Protection F. Regulatory Constraints G. Decentralized Testing Market Challenges VI. Worldwide Market and Technology Review A. DNA Sequencing 1. Introduction 2. Sequencing Methods 3. Autoradiography 4. The Human Genome Project 5. Sequencing Automation 6. Image Scanners 7. Fluorescent Detection 8. Gene Profiling 9. Gene Expression 10. Polymorphism Screening 11. Protein Interaction Networks B. DNA and RNA Probe Technologies 1. Basic Principles 2. Probe Preparation 3. The DNA Probe Test 4. Test Formats 5. Labeling Techniques 6. Amplification Methods C. Detection Technologies 1. Radioactive Methods a. Overview b. Major Isotopes P-32 S-35 H-3 I-125 2. Non-Isotopic Methods a. Enzymatic Labels b. Chemical Labeling O Indirect Chemical Labeling O Direct Chemical Labeling c. Fluorescence d. Chemiluminescence e. Electrical Conductivity D. Molecular Diagnostic Instrumentation Review 1. Abbott LCx 2. Beckman Coulter/Biomek FK 3. BD Viper System with XTR Technology 4. BD Innova 5. Becton Dickinson SDA 6. bioMerieux NucliSENS easyMAG 7. bioMerieux NucliSENS easyQ and MiniMAG 8. Bio-Rad GeneScope 9. Cepheid GeneXpert 10. Curetis Unyvero 11. GenMark Dx eSensor XT-8 12. Hologic/Gen-Probe Panther 13. Hologic/Gen-Probe Tigris/DTS 14. HTG Molecular Edge 15. Life Technologies QuantStudio Dx 16. Qiagen QIAsymphony RGQ 17. Roche Cobas Amplicor 18. Roche Cobas TaqMan 48 19. Roche Cobas TaqMan 20. Roche Cobas TaqMan AmpliPrep 21. Roche LighCycler 480 22. Roche Cobas 4800 23. Roche Cobas s 201 24. Siemens Versant 25. Tecan LS Series E. Biochips: Genosensors, Microarrays, and Labs-on-the-Chip - Liquid Transportation and Mixing - Separation - Reaction - Detection F. Pharmacogenomics G. Major Applications 1. Microbiology/Infectious Diseases a. Overview b. Major Infectious Diseases AIDS: HIV/HIV-1/2/Combo, HIVAg/HIV NAT,Western Blot, HTLV-I/II Adenovirus Aeromonas Anthrax/Bacillus Anthracis Arboviruses Babesiosis Bacillary Epithelioid Angiomatosis (BEA) and Other Bartonella (Rochalimaea) Blastocystis Hominis Brucella Campylobacter Candida Chagas Disease Chancroid Chlamydia Clostridium Difficile Coronaviruses Coxsackieviruses Creutzfeldt-Jakob’s Disease Cryptosporidium Parvum Cyclospora Cayetanensis Cytomegalovirus Ebola Virus E. Coli EchoVirus Encephalitis Enteroviruses Epstein-Barr Virus Giardia Lamblia Gonorrhea Granuloma Inguinale Hantavirus Helicobacter Pylori Hepatitis: HAV NAT, HBV NAT, HBs Ag, HCV, HCV NAT,Anti-HBc, Anti-HBs, Anti-HAV, Hepatitis Delta, HBc Ag,HBe Ag, ALT/SGPT Herpes Simplex Virus Human Herpes Virus-6 (HHV-6) Influenza Viruses Legionella Lyme Disease Lymphogranuloma Venereum (LGV) Malaria Measles (Rubeola) Meningitis Microsporidium Mononucleosis Mumps Mycoplasma Papillomaviruses Parvovirus B19 Pneumonia Polyomaviruses Pseudomonas Aeruginosa Rabies Respiratory Syncytial Virus (RSV) Rhinoviruses Rotavirus Rubella Salmonellosis Septicemia Shigellosis Staphylococcus Aureus Streptococci Syphilis Toxoplasmosis Trichomonas Vaginalis Tuberculosis Vibrio West Nile Virus Yersina 2. Cancer Testing a. Overview b. Major Cancer Types * Prostate * Lung * Colon and Rectum * Breast * Skin * Uterine * Leukemia * Oral c. Oncogenes Abl/abl-bcr AIB1 BCL-2 BRCA1 CD44 C-fos C-myb C-myc CYP17 Erb-B HPC1 N-myc P40 P51 P53 PIK3CA PTI-1 Ras Reg Sis Src 3. Genetic Diseases a. Overview b. Nucleic Acid Amplification c. Chromosome Imaging d. Genomics Technologies e. Proteomics Technologies f. Current Pharmacogenomic Tests g. Future Pharmacogenomic Testing h. Major Diseases * Achondroplasia * Autosomal Dominant Polycystic Kidney Disease * Cancer * Cosmetogenomics * Cystic Fibrosis * Down's Syndrome * Duchenne and Becker Muscular Dystrophy * Factor V (Leiden) * Factor IX Deficiency * Fragile X Syndrome * Heart Disease * Hemochomatosis * Hemophilia * Huntington's Disease * Maternal-Fetal Incompatibility * Multiple Endocrine Neoplasia * Phenylketonuria (PKU) * Polycystic Kidney Disease (PKD) * Prenatal Screening * Retinitis Pigmentosa * Retinoblastoma * Sickle Cell Anemia * Spinal Muscular Atrophy * Vitamin B12 Metabolism i. Social Issues and Concerns 4. Forensic Testing a. Overview b. Multilocus and Single Locus Probes * Multilocus Probes * Single Locus Probes * PCR and RFLP c. The FBI d. DNA Profile Data Banks * U.S.A. * U.K. e. Judicial Implementation f. Major Crime Categories g. Factors Contributing to the DNA Probe Market Expansion * Technology Availability * Use of Hair as Evidence h. Wildlife Forensics 5. Paternity Testing/HLA Typing 6. Other Applications a. Disease Susceptibility Testing b. Cardiovascular Diseases c. Diabetes d. Alzheimer's Disease e. Periodontal Disease f. Plasma Purification g. Organ Transplantation h. Water Contamination i. Other H. Competing/complementing 1. Monoclonal Antibodies/Immunoassays 2. RNA Probes 3. Two-Dimensional Electrophoresis 4. Flow Cytometry VII. France Molecular Diagnostics Market A. Executive Summary B. Business Environment C. Market Structure D. Market Size, Test Volume and Sales Forecasts, Major Supplier Sales and Market Shares VIII. Competitive Assessments - Abbott - Affymetrix - Agilent Technologies - Applied Gene Technologies - Arca Biopharma - Beckman Coulter/Danaher - Becton Dickinson - Biokit - bioMerieux - Bio-Rad - Biotest - Cepheid - CellMark Forenciscs/LabCorp - Decode Genetics - Diadexus - Eiken - Elitech Group - Enzo - Exact Sciences - Fujirebio - Grifols - Hologic/Gen-Probe - Illumina - Kreatech/Leica - Li-Cor Biosciences - Monogram Biosciences/LabCorp - Myriad Genetics - Ortho-Clinical Diagnostics - Perkin Elmer/Caliper - Proteome Sciences - Qiagen - Roche - Scienion - Sequenom - Shimadzu - Siemens - Sierra Molecular - Takara Bio - Tecan Group - Thermo Fisher XIII. Appendix: Major Universities and Research Centers Developing Molecular Diagnostic Technologies List of Tables Major Companies Developing or Marketing AIDS Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Adenovirus Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Bartonella Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Campylobacter Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Candida Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Chlamydia Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Clostridium Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Coronavirus Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Cryptosporidium Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing CMV Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Echovirus Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Enterovirus Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing EBV Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Giardia Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Gonorrhea Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Hantavirus Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Helicobacter Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Hepatitis Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Herpes Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Influenza Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Legionella Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Lyme Disease Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Measles Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Meningitis Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Mononucleosis Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Mumps Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Mycoplasma Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Pneumonia Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing RSV Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Rotavirus Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Rubella Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Salmonella Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Septicemia Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Shigella Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Streptococci Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Syphilis Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Toxoplasmosis Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Trichomonas Molecular Diagnostic and Other Direct Identification Tests Major Companies Developing or Marketing Tuberculosis Molecular Diagnostic and Other Direct Identification Tests Oncogenes Potential Application in Cancer Diagnosis Major Companies Developing or Marketing Cancer Molecular Diagnostic Tests Major Companies Developing or Marketing Molecular Diagnostic Tests For Genetic Diseases France Molecular Diagnostics Test Volume And Sales By Major Application 2014-2019 France Laboratories Performing DNA Sequencing By Market Segment 2014 France Molecular Diagnostics Market Potential Laboratory Universe by Market Segment 2014 France Molecular Diagnostics Test Volume By Major Application 2014-2019 France Major Infectious Disease Test Volume by Assay 2014-2019 France Major Infectious Disease Test Volume by Method 2014 France Molecular Diagnostics Market By Major Application 2014-2019 France Molecular Diagnostics Market Estimated Sales And Market Shares of Major Suppliers 2014 France Major Infectious Disease Diagnostics Market by Assay 2014-2019 France AIDS Testing Market Estimated Sales by Major Supplier 2014 France Adenovirus Testing Market Estimated Sales by Major Supplier 2014 France Chlamydia Testing Market Estimated Sales by Major Supplier 2014 France CMV Testing Market Estimated Sales by Major Supplier 2014 France Gonorrhea Testing Market Estimated Sales by Major Supplier 2014 France Hepatitis Testing Market Estimated Sales by Major Supplier 2014 France Hepatitis C Testing Market Estimated Sales by Major Supplier 2014 France HIV/Hepatitis Blood Screening NAT Market Reagent Sales by Major Supplier 2014 France Herpes Testing Market Estimated Sales by Major Supplier 2014 France Influenza Testing Market Estimated Sales by Major Supplier 2014 France Meningitis Testing Market Estimated Sales by Major Supplier 2014 France Mycoplasma Testing Market Estimated Sales by Major Supplier 2014 France RSV Testing Market Estimated Sales by Major Supplier 2014 France Shigella Testing Market Estimated Sales by Major Supplier 2014
