RNAi Technologies and Global Markets

 Published On: Jan, 2016 |    No of Pages: 176 |  Published By: BCC Research | Format: PDF
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The global market for RNA Interference technologies is expected to grow from $262.1 million in 2015 to $392.6 million in 2020, registering a compound annual growth rate (CAGR) of 8.4%.

This report provides:

-An overview of the global market for RNAi technologies which are used in the areas of drug delivery, therapeutics, and diagnostics
-Analyses of global market trends, with data from 2014, estimates for 2015, and projections of compound annual growth rates (CAGRs) through 2020
-A breakdown of the technologies: RNAi for drug delivery (by nanoparticle delivery, nucleic acid delivery, aptamer delivery); RNAi for drug discovery and therapeutics (by diseases); RNAi for disease diagnostics and biomarker development (by diseases); and RNAi for reagents, research tools, and other applications (by application)
-Examination of significant deals in the RNAi technologies sector during the last decade
-A look at commercial opportunities in the RNAi research tools and reagents, drug development, diagnostic, and agriculture markets
-Profiles of major players in the industry

INTRODUCTION

STUDY OBJECTIVES
BCC Research conducted this report to analyze the market prospects of ribonucleic acid interference (RNAi) technology. The report assesses the progress of new RNAi techniques in the areas of research tools and products, therapeutics, diagnostics and agricultural segments. Further, the report evaluates the product usage, research and development, collaborations, market trends and future applications, prospects, challenges, etc. in the RNAi market.

Global RNAi technology is in its nascent state. However, the market holds significant opportunities due to the promising application of RNAi therapeutics in often-fatal diseases like cancer, heart ailments, autoimmune diseases, neurodegenerative disease and others. The RNAi research tools and reagents market is growing well due to its major applications in RNAi therapeutics, diagnostics and agricultural areas. Secondly, various RNAi therapeutics candidates are showing success in advanced stages of their clinical investigations. Further, the availability of RNAi diagnostics tests offer great promises of successful application of RNAi therapeutics and diagnostics in medical settings.

The market projections are based on the commercialized research products and tools and trends in their applications, product development, applications in diagnostics, and investments for RNAi therapeutics, agricultural products and other areas. The report provides present market analysis as well as a projection for the next five years (until 2020). The report includes market analysis, market leaders, manufacturers and market shares, profiles of leading companies, current situations, new developments, patent analysis, regulatory aspects, drivers and other factors of RNAi market.

REASONS FOR DOING THIS STUDY
The RNAi market is burgeoning and is one of the most watched markets in the pharmaceuticals industry. The reason for this status is the encouraging application of RNAi mechanisms in therapeutics through gene silencing. There is no approved therapy so far; however, various candidates have shown successful results in their clinical investigations. The report reflects the details of those candidates along with prospective applications of RNAi in diagnostics and agriculture. This market will grow through 2020 with the successful utilization of techniques in both therapeutics and agriculture.

CONTRIBUTIONS OF THE STUDY AND INTENDED AUDIENCE
The report summarizes the market movements, progress and innovations in the evolving RNAi technology market. The report also accentuates the advancement and prospective application of RNAi mechanisms in different sectors. RNAi technologies are expected to be advantageous for pharmaceutical /  biopharmaceutical/medical/clinical/diagnostics/agriculture/food as well as other industries including tools/technology/product/platform manufacturers and reagent manufacturers. This study may benefit the business planners in companies, scientists, researchers, research organizations, governmental and non-governmental organizations and others.

SCOPE OF THE STUDY
BCC Research conducted the market assessment, the global and regional breakdown of sales data, market projection for the commercial RNAi technologies, application of the techniques in commercial sector as well as in research and development. Further, BCC Research offers the details of new developments, patent analysis, market leaders and market share, etc. for the RNAi technologies and its applications.

The report summarizes the global RNAi technologies market by category and by region. The RNAi market is analyzed based on RNAi research tools and reagents as well as on RNAi diagnostics. The research tools and reagents and therapeutics considered in this report are mainly for small/short interfering RNAs (siRNAs) and diagnostics are mainly based on microRNAs (miRNAs).

MicroRNA (miRNA) research tools, services, drug discovery etc. are excluded from this report; however, these areas are worth a separate report and thus are analyzed in BCC Research report BIO115B in detail. U.S. and non-U.S. markets are considered for the geographical market analysis. The prospective application of RNAi therapeutics in various disease classifications such as oncological, cardiovascular, neurodegenerative, ophthalmologic and others are discussed. The application and progress of RNAi technologies in agriculture is also discussed in this report.

BCC Research verified the sales data for the global and regional RNAi markets for the present and projected values through statistical analysis. The tools/technology details in the report are based on their present and their prospective application and suitability.

METHODOLOGY
BCC Research collected relevant information for this RNAi technology report using both primary and secondary research methodologies along with other sources of information. BCC interviewed industry experts, representatives, domain experts, practice leaders, scientists and other experts from the industry to collect information. The revenue and sales data for the RNAi tools/technologies/ products/platforms are gathered from company annual reports, financial news and other relevant data sources. Market analysis and projection are based on the probable unit prices, usage of the particular RNAi tools/reagents, current global economic status and probable application of RNAi technologies for commercial implementations and for research and development (R&D).

INFORMATION SOURCES
BCC Research examined relevant companies and other related sources to gather data for the RNAi technology market. BCC Research met with company spokespersons, representatives and research teams to obtain details of the technologies and their market application.

BCC Research reviewed company annual reports, company literature and financial results, research papers and articles, company white papers, pharmaceutical and other newsletters, agricultural articles, science digests, patent files, scientific journals, medical papers and journals, booklets, government-published documents, online medical libraries, medical and pharmaceutical blogs, news feeds, newsletters, product literature, periodicals, abstracts, technical articles, bulletins, and pharmaceutical, biopharmaceutical and medicine databases, etc.
Chapter- 1: INTRODUCTION - Complimentary 4 $0
STUDY OBJECTIVES
REASONS FOR DOING THIS STUDY
CONTRIBUTIONS OF THE STUDY AND INTENDED AUDIENCE
SCOPE OF THE STUDY
METHODOLOGY
INFORMATION SOURCES
ANALYST CREDENTIALS
RELATED BCC RESEARCH REPORTS
BCC RESEARCH WEBSITE
DISCLAIMER

Chapter- 2: EXECUTIVE SUMMARY 2 $250
Table Summary : GLOBAL REVENUE FOR RNA INTERFERENCE TECHNOLOGIES BY TYPE, THROUGH 2020
Figure Summary : GLOBAL REVENUE FOR RNA INTERFERENCE TECHNOLOGIES BY TYPE, 2013-2020

Chapter- 3: OVERVIEW     28     $1587
RIBONUCLEIC ACID (RNA)
RNA INTERFERENCE (RNAI)
RNA INTERFERENCE DRUG DELIVERY
RNAI DRUG DISCOVERY AND DEVELOPMENT
OTHER POTENTIAL APPLICATIONS OF RNA INTERFERENCE

Chapter- 4: NEW DEVELOPMENTS AND REGULATORY ACTIVITY 8 $453
NEW DEVELOPMENTS
REGULATORY ASPECTS
COLLABORATIVE TRIALS AND FUTURE ACTIVITIES

Chapter- 5: MARKET ANALYSIS 53 $3004
MARKET BY TECHNOLOGY
MARKET BY REGION

Chapter- 6: INDUSTRY STRUCTURE     9 $510
RNAI RESEARCH TOOLS AND REAGENTS
RNAI DIAGNOSTICS

Chapter- 7: PATENT ANALYSIS 9 $510
PATENTS BY YEAR
PATENTS BY COUNTRY FOR RNA INTERFERENCE TECHNOLOGIES
PATENTS BY COMPANY FOR RNA INTERFERENCE TECHNOLOGIES
PATENTS BY ASSIGNEE FOR RNA INTERFERENCE TECHNOLOGIES

Chapter- 8: CURRENT STATUS 22 $1247
INNOVATIVE TECHNOLOGIES AND PLATFORMS FOR RNA INTERFERENCE
FACTORS AFFECTING THE RNA INTERFERENCE MARKET
CURRENT DRIVERS FOR THE RNA INTERFERENCE TECHNOLOGY MARKET
MERGER AND ACQUISITION ACTIVITIES
FUNDING FOR DEVELOPMENT OF RNA INTERFERENCE THERAPEUTICS AND TECHNOLOGIES

Chapter- 9: COMPANY PROFILES 36 $2040
ADVIRNA
ALNYLAM PHARMACEUTICALS, INC.
APEIRON BIOLOGICS AG
APPLIED BIOLOGICAL MATERIALS, INC.
ARBUTUS BIOPHARMA CORP. (PREVIOUSLY TEKMIRA PHARMACEUTICALS CORP.)
ARCTURUS THERAPEUTICS, INC.
ARROWHEAD RESEARCH CORP.
ASCLETIS INC.
BENITEC BIOPHARMA LTD.
BIOGEN IDEC, INC.
BIOMICS BIOTECHNOLOGIES CO. LTD.
BIONEER CORP.
CELLECTA, INC.
CERULEAN PHARMA, INC.
DICERNA PHARMACEUTICALS, INC.
EXIQON A/S
F. HOFFMANN-LA ROCHE AG (ROCHE)
GENERAL ELECTRIC CO.
INTEGRATED DNA TECHNOLOGIES, INC.
INVIVOGEN
ISIS PHARMACEUTICALS, INC.
MARINA BIOTECH, INC.
MODERNA THERAPEUTICS
MONSANTO CO.
NITTO DENKO CORP.
PEPTIMED INC.
QIAGEN N.V.
QUARK PHARMACEUTICALS, INC.
REGULUS THERAPEUTICS
ROSETTA GENOMICS LTD.
RXI PHARMACEUTICALS CORP.
SANOFI
SIGMA-ALDRICH
SILENCE THERAPEUTICS PLC.
SILENSEED LTD.
SOLSTICE BIOLOGICS
SOMAGENICS, INC.
SUMITOMO DAINIPPON PHARMA CO. LTD.
SYNGENTA INTERNATIONAL AG
THE NATIONAL INSTITUTES OF HEALTH (NIH)
THE RNAI CONSORTIUM AT BROAD INSTITUTE OF MIT AND HARVARD
THE UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER
THERMO FISHER SCIENTIFIC, INC.
ZELTIA GROUP

Chapter- 10: APPENDIX  5  $283
GLOSSARY AND ABBREVIATIONS

List of Tables

Summary Table : GLOBAL REVENUE FOR RNA INTERFERENCE TECHNOLOGIES BY TYPE, THROUGH 2020
Table 1 : EVOLUTION OF RNA
Table 2 : MICRORNA (MIRNA) DATABASES
Table 3 : SHORT/SMALL INTERFERING RNA (SIRNA) DATABASES
Table 4 : PIWI-INTERACTING RNA (PIRNA) DATABASES
Table 5 : STABILIZATION METHODS FOR LIPID BASED SIRNA DELIVERY SYSTEM
Table 6 : NEW DEVELOPMENTS IN THE RESEARCH PIPELINE OF RNAI THERAPEUTICS AND TECHNOLOGIES AS OF SEPTEMBER 2015
Table 7 : GLOBAL REVENUE FOR RNAI TECHNOLOGIES BY TYPE, THROUGH 2020
Table 8 : MARKET SHARE OF RNAI TECHNOLOGIES BY TYPE, 2014
Table 9 : MODIFICATIONS OF SIRNA
Table 10 : RNAI VECTORS
Table 11 : GLOBAL REVENUE FOR RNAI RESEARCH TOOLS AND REAGENTS, THROUGH 2020
Table 12 : MARKET SHARE OF RNAI RESEARCH TOOLS AND REAGENTS, 2014
Table 13 : DISEASE-SPECIFIC TARGET GENES/PROTEINS FOR RNAI THERAPEUTICS
Table 14 : GLOBAL PHARMACEUTICAL MARKET, THROUGH 2020
Table 15 : GLOBAL PHARMACEUTICAL MARKET SHARES BY REGION, 2014
Table 16 : TOP GLOBAL PHARMACEUTICAL COMPANIES BY SALES, 2014
Table 17 : GLOBAL OUTLOOK OF THERAPEUTIC SPENDING BY DISEASE, THROUGH 2018
Table 18 : NUMBER OF PUBLICATIONS ASSOCIATED WITH MIRNA AND DISEASES, OCTOBER 2015
Table 19 : MIRNA IN VARIOUS CANCER TYPES
Table 20 : MIRNA AND TARGET GENE PAIRS IN VARIOUS CANCER TYPES
Table 21 : BIOMARKERS IN VARIOUS CANCER TYPES
Table 22 : GLOBAL REVENUE MARKET FOR RNAI DIAGNOSTICS, THROUGH 2020
Table 23 : GLOBAL REVENUE FOR MIRNA RESEARCH TOOLS, THROUGH 2020
Table 24 : SAFETY ISSUES WITH RNAI CROP IMPROVEMENT
Table 25 : PLANT IMPROVEMENT AREAS THROUGH RNAI TECHNOLOGIES
Table 26 : REGIONS, GENES AND APPLICATION OF RNAI-TARGETING ORGANISMS FOR IMPROVEMENT OF CROPS
Table 27 : GLOBAL REVENUE FOR RNAI RESEARCH TOOLS AND REAGENTS BY REGION, THROUGH 2020
Table 28 : GLOBAL MARKET SHARE OF RNAI RESEARCH TOOLS AND REAGENTS BY REGION, 2014
Table 29 : GLOBAL REVENUE FOR RNAI DIAGNOSTICS BY REGION, THROUGH 2020
Table 30 : GLOBAL MARKET SHARE OF RNAI DIAGNOSTICS BY REGION, 2014
Table 31 : LEADING MANUFACTURERS/SUPPLIERS OF RNAI RESEARCH TOOLS AND REAGENTS, 2014
Table 32 : GLOBAL MARKET SHARES OF MANUFACTURERS/SUPPLIERS FOR RNAI RESEARCH TOOLS AND REAGENTS, 2014
Table 33 : LEADING MANUFACTURERS/SUPPLIERS OF RNAI DIAGNOSTICS, 2014
Table 34 : MARKET SHARES OF MANUFACTURERS/SUPPLIERS FOR RNAI DIAGNOSTICS, 2014
Table 35 : TOTAL NUMBER OF PATENTS BY YEAR, 2013-AUGUST 2015
Table 36 : NUMBER OF U.S. PATENTS FOR RNAI TECHNOLOGIES BY COUNTRY, 2013-AUGUST 2015
Table 37 : PATENT SHARES FOR RNAI TECHNOLOGIES BY COUNTRY, 2013-AUGUST 2015
Table 38 : NUMBER OF U.S. PATENTS FOR RNAI TECHNOLOGIES BY COMPANY, 2013-AUGUST 2015
Table 39 : NUMBER OF PATENTS FOR RNAI TECHNOLOGIES BY TYPE OF ASSIGNEE, 2013-AUGUST 2015
Table 40 : FUNDING FOR DEVELOPMENT OF RNAI-BASED PRODUCTS AND PLATFORMS, 2013-SEPTEMBER 2015
Table 41 : INVESTMENTS FOR DEVELOPMENT OF RNAI-BASED PRODUCTS AND PLATFORMS, 2013-SEPTEMBER 2015

List of Figures

Summary Figure : GLOBAL REVENUE FOR RNA INTERFERENCE TECHNOLOGIES BY TYPE, 2013-2020
Figure 1 : GLOBAL REVENUE FOR RNAI TECHNOLOGIES BY TYPE, 2013-2020
Figure 2 : MARKET SHARE OF RNAI TECHNOLOGIES BY TYPE, 2014
Figure 3 : GLOBAL REVENUE FOR RNAI RESEARCH TOOLS AND REAGENTS, 2013-2020
Figure 4 : MARKET SHARE OF RNAI RESEARCH TOOLS AND REAGENTS, 2014
Figure 5 : GLOBAL PHARMACEUTICAL SALES MARKET,2013-2020
Figure 6 : GLOBAL PHARMACEUTICAL MARKET SHARES BY REGION, 2014
Figure 7 : GLOBAL REVENUE MARKET FOR RNAI DIAGNOSTICS, 2013-2020
Figure 8 : GLOBAL REVENUE FOR MIRNA RESEARCH TOOLS,2013-2020
Figure 9 : GLOBAL REVENUE FOR RNAI RESEARCH TOOLS AND REAGENTS BY REGION, 2013-2020
Figure 10 : GLOBAL MARKET SHARE OF RNAI RESEARCH TOOLS AND REAGENTS BY REGION, 2014
Figure 11 : GLOBAL REVENUE FOR RNAI DIAGNOSTICS BY REGION, 2013-2020
Figure 12 : GLOBAL MARKET SHARE OF RNAI DIAGNOSTICS BY REGION, 2014
Figure 13 : GLOBAL MARKET SHARES OF MANUFACTURERS/SUPPLIERS FOR RNAI RESEARCH TOOLS AND REAGENTS, 2014
Figure 14 : MARKET SHARES OF MANUFACTURERS/SUPPLIERS FOR RNAI DIAGNOSTICS, 2014
Figure 15 : TOTAL NUMBER OF PATENTS BY YEAR, 2013-AUGUST 2015
Figure 16 : PATENT SHARES FOR RNAI TECHNOLOGIES BY COUNTRY, 2013-AUGUST 2015
Figure 17 : NUMBER OF PATENTS FOR RNAI TECHNOLOGIES BY TYPE OF ASSIGNEE, 2013-AUGUST, 2015

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