Prefilled Syringes Global Market – Forecast To 2028

Abstract

Prefilled syringes are the immediate packaging systems or self-contained drug delivery systems that are used to encase and deliver injectable pharmaceutical products used for treating communicable and non-communicable diseases, preventing infectious diseases and enhancing the diagnostic accuracy of diagnostic procedures. These primary containers that have evolved to become the status-quo device among the pharmaceutical companies through the incorporation of proprietary features to improve administration of a therapy, clinical outcomes and regulatory claims help the firms to further protect or regain their revenue streams during the mature years of pharmaceutical products lifecycle.

As estimated by IQ4I analysis, the prefilled syringes global market is expected to grow at a high single digit CAGR to reach $10,273.8 million by 2028 due to the escalating popularity of prefillable syringes among patients and healthcare professionals, elevating propensity of pharmaceutical companies towards prefillable syringes for economical brand differentiation, preferential adoption of prefilled syringes for the delivery of various highly viscous and sensitive biologic products, emergence of technologically advanced prefillable syringe products, persistently escalating prevalence of chronic and infectious diseases and allergies, increasing number of prefillable syringes being approved by regulatory authorities across the globe and the trend of collaboration and investments among the prefillable syringe manufacturers.

The prefilled syringes global market is categorized into various market segments based on the material, design, closure system, application, product, usability, molecule type, route of administration and geography.

The prefilled syringes global market based on material is segmented into glass based prefilled syringes and polymer based prefilled syringes. Among these, glass based prefilled syringes segment commanded the largest revenue in 2021 and is expected to grow at a high single digit CAGR from 2021 to 2028. Polymer based prefilled syringes segment is the fastest emerging segment and is expected to grow at a double digit CAGR from 2021 to 2028.

The prefilled syringes global market based on design is grouped into single chamber prefilled syringes and dual chamber prefilled syringes. Among these, single chamber prefilled syringes segment commanded the largest revenue in 2021 and is expected to grow at a high single digit CAGR from 2021 to 2028. Dual chamber prefilled syringes segment is the fastest emerging segment and is expected to grow at a double digit CAGR during the forecasted period.

The prefilled syringes global market based on closure system is classified into staked needle prefilled syringes, luer lock prefilled syringes and non-luer lock prefilled syringes. Among these, staked needle prefilled syringes segment commanded the largest revenue in 2021 and is also the fastest growing segment that is expected to grow at a high single digit CAGR from 2021 to 2028.

The prefilled syringes global market based on application is categorized into heparin prefilled syringes, vaccines prefilled syringes, therapeutic drugs prefilled syringes, diluents prefilled syringes, surgical application prefilled syringes, hyaluronic acid prefilled syringes and other prefilled syringes applications (other anticoagulant prefilled syringes, saline flush prefilled syringes and contrast imaging agents prefilled syringes). Among these, heparin prefilled syringes segment commanded the largest revenue in 2021 and is expected to grow at a mid-single digit CAGR from 2021 to 2028. Therapeutic drugs prefilled syringes segment is the fastest emerging segment and is expected to grow at a low teen CAGR from 2021 to 2028.

The prefilled syringes global market based on product is divided into complete prefilled syringes, consumables (needles) and accessory devices (autoinjectors, syringe pumps, wearable injectors). Among these, complete prefilled syringes segment accounted for the largest revenue in 2021 and is expected to grow at a high single digit CAGR from 2021 to 2028. Accessory devices segment is the fastest emerging segment and is expected to grow at a high single digit CAGR from 2021 to 2028. Complete prefilled syringes segment based on product type is further segregated into conventional prefilled syringes and safety prefilled syringes. Among these, safety prefilled syringes segment accounted for the largest revenue in 2021 and is also the fastest growing segment that is expected to grow at a high single digit CAGR from 2021 to 2028.

The prefilled syringes global market based on usability is bifurcated into disposable prefilled syringes and reusable prefilled syringes. Among these, disposable prefilled syringes segment commanded the largest revenue in 2021 and is also the fastest growing segment that is expected to grow at a high single digit CAGR from 2021 to 2028.

The prefilled syringes global market based on molecule type is segmented into large molecule prefilled syringes and small molecule prefilled syringes. Among these, large molecule prefilled syringes segment accounted for the largest revenue in 2021 and is also the fastest emerging segment that is expected to grow at a high single digit CAGR from 2021 to 2028.

The prefilled syringes global market based on route of administration is segregated into subcutaneous prefilled syringes, intramuscular prefilled syringes, intravenous prefilled syringes and other routes prefilled syringes (intra-articular prefilled syringes, intra-vitreal prefilled syringes, topical prefilled syringes). Among these, subcutaneous prefilled syringes segment accounted for the largest revenue in 2021 and is also the fastest growing segment that is expected to grow at a high single digit CAGR from 2021 to 2028.

The report provides an in-depth market analysis of the above-mentioned segments across the following regions:

North America
U.S.
Rest of North America
Europe
Germany
France
Italy
Rest of Europe
Asia-Pacific
China
Japan
India
Rest of APAC
Rest of the World (RoW)
Brazil
Rest of LATAM
Middle East and Africa (MEA)

Content

Table of Contents

1 EXECUTIVE SUMMARY 24
2 INTRODUCTION 37
2.1 KEY TAKEAWAYS 37
2.2 SCOPE OF THE REPORT 38
2.3 REPORT DESCRIPTION 38
2.4 MARKETS COVERED 41
2.5 STAKEHOLDERS 43
2.6 RESEARCH METHODOLOGY 43
2.6.1 MARKET SIZE ESTIMATION 47
2.6.2 MARKET BREAKDOWN AND DATA TRIANGULATION 49
2.6.3 SECONDARY SOURCES 50
2.6.4 PRIMARY SOURCES 50
2.6.5 KEY DATA POINTS FROM SECONDARY SOURCES 51
2.6.6 KEY DATA POINTS FROM PRIMARY SOURCES 52
2.6.7 ASSUMPTIONS 53
2.6.8 AVERAGE SELLING PRICE (ASP) OF PREFILLED SYRINGES AND HEPARIN PREFILLED SYRINGES, (2021) ($) 54
3 MARKET ANALYSIS 55
3.1 INTRODUCTION 55
3.2 MARKET SEGMENTATION 57
3.3 FACTORS INFLUENCING MARKET 60
3.3.1 DRIVERS AND OPPORTUNITIES 61
3.3.1.1 Increasing popularity of Prefilled Syringes among patients and
healthcare professionals 61
3.3.1.2 Increasing inclination of pharmaceutical companies towards prefilled syringes for injectable drug product cost-savings and
brand differentiation 62
3.3.1.3 Preferential adoption of prefilled syringes for the delivery of biologics 64
3.3.1.4 Emergence of technologically advanced products 66
3.3.1.5 Escalating prevalence of Chronic and Infectious diseases and Allergies 68
3.3.1.6 Increasing regulatory approvals of prefilled syringes 71
3.3.1.7 Collaborations and Investments to open an array of opportunities for
the market to flourish 72
3.3.2 RESTRAINTS AND THREATS 73
3.3.2.1 Technical challenges associated with manufacturing process of
prefillable syringes 73
3.3.2.2 Increasing concerns about the interaction of prefillable syringe
components with drug products 75
3.3.2.3 Availability of less expensive and non-invasive medication alternatives 77
3.3.2.4 Stringent international standards and regulatory guidelines to followed
by prefillable syringe manufacturers 78
3.3.2.5 Threat of Recalls of Prefilled Syringes 82
3.4 REGULATORY AFFAIRS 87
3.4.1 INTERNATIONAL ORGANIZATION FOR STANDARDIZATION 87
3.4.1.1 ISO 11040-4:2015 (PART 4): GLASS BARRELS FOR INJECTABLES AND STERILIZED SUBASSEMBLED SYRINGES READY FOR FILLING 87
3.4.1.2 ISO 11040-5:2012 (PART 5): PLUNGER STOPPERS FOR INJECTABLES 88
3.4.1.3 ISO 11040-6:2019 (PART 6): PLASTIC BARRELS FOR INJECTABLES
AND STERILIZED SUBASSEMBLED SYRINGES READY FOR FILLING 88
3.4.1.4 ISO 23908:2011: SHARPS PROTECTION FEATURES FOR SINGLE-USE HYPODERMIC NEEDLES, INTRODUCERS FOR CATHETERS AND
NEEDLES USED FOR BLOOD SAMPLING 88
3.4.1.5 ISO 80369-20:2015: SMALL-BORE CONNECTORS FOR LIQUIDS AND GASES IN HEALTHCARE APPLICATIONS 89
3.4.2 U.S. 89
3.4.3 CANADA 91
3.4.4 EUROPE 94
3.4.5 JAPAN 97
3.4.6 CHINA 99
3.4.7 INDIA 100
3.5 PORTER’S FIVE FORCE ANALYSIS 101
3.5.1 THREAT OF NEW ENTRANTS 102
3.5.2 THREAT OF SUBSTITUTES 104
3.5.3 BARGAINING POWER OF SUPPLIERS 106
3.5.4 BARGAINING POWER OF BUYERS 107
3.5.5 COMPETITIVE RIVALRY 108
3.6 SUPPLY CHAIN ANALYSIS 110
3.7 TECHNOLOGICAL ADVANCEMENTS 121
3.7.1 INTRODUCTION 121
3.7.2 PREFILLABLE SYRINGES FOR DEEP COLD STORAGE OF VACCINES 122
3.7.3 REUSABLE OR MULTIDOSE PREFILLABLE SYRINGES 122
3.7.4 TABLET-IN-SYRINGE 122
3.8 PATENT TRENDS 123
3.9 CLINICAL TRIALS 125
3.10 SALES VOLUME OR NUMBER OF UNITS OF PREFILLED SYRINGES 128
3.10.1 PREFILLED SYRINGES NUMBER OF UNITS BASED ON REGION AND COUNTRY 128
3.10.2 HEPARIN PREFILLED SYRINGES NUMBER OF UNITS BASED ON
REGION AND COUNTRY 132
3.11 IMPACT OF COVID-19 ON PREFILLED SYRINGES 136
3.12 MARKET SHARE ANALYSIS BASED ON MAJOR PLAYERS 138
3.12.1 PREFILLED SYRINGES GLOBAL MARKET SHARE ANALYSIS 138
3.13 PREFILLED SYRINGES COMPANY COMPARISON TABLE BY REVENUE,
PRODUCT AND PRODUCT PRODUCT TYPE 143
4 PREFILLED SYRINGES GLOBAL MARKET, BASED ON MATERIAL 153
4.1 INTRODUCTION 153
4.2 GLASS BASED PREFILLED SYRINGES 157
4.3 POLYMER BASED PREFILLED SYRINGES 163
5 PREFILLED SYRINGES GLOBAL MARKET, BASED ON DESIGN 169
5.1 INTRODUCTION 169
5.2 SINGLE CHAMBER PREFILLED SYRINGES 173
5.3 DUAL CHAMBER PREFILLED SYRINGES 179
6 PREFILLED SYRINGS GLOBAL MARKET, BASED ON CLOSURE SYSTEM 184
6.1 INTRODUCTION 184
6.2 STAKED NEEDLE PREFILLED SYRINGES 187
6.3 LUER LOCK PREFILLED SYRINGES 193
6.4 NON-LUER LOCK PREFILLED SYRINGES 198
7 PREFILLED SYRINGES GLOBAL MARKET, BASED ON PRODUCT 202
7.1 INTRODUCTION 202
7.2 COMPLETE PREFILLED SYRINGES 206
7.2.1 CONVENTIONAL PREFILLED SYRINGES 211
7.2.2 SAFETY PREFILLED SYRINGES 214
7.3 CONSUMABLES (NEEDLES) 218
7.4 ACCESSORY DEVICES (AUTOINJECTORS, WEARABLE INJECTORS AND
SYRINGE PUMPS) 223
8 PREFILLED SYRINGES GLOBAL MARKET, BASED ON APPLICATION 230
8.1 INTRODUCTION 230
8.2 HEPARIN PREFILLED SYRINGES 234
8.3 VACCINES PREFILLED SYRINGES 241
8.4 THERAPEUTIC DRUGS PREFILLED SYRINGES 246
8.5 DILUENTS PREFILLED SYRINGES 255
8.6 SURGICAL APPLICATION (ANAESTHETIC AGENTS, SURGICAL SEALANTS) PREFILLED SYRINGES 258
8.7 HYALURONIC ACID PREFILLED SYRINGES 263
8.8 OTHER PREFILLED SYRINGE APPLICATIONS (OTHER ANTICOAGULANT PREFILLED SYRINGES, SALINE FLUSH PREFILLED SYRINGES AND CONTRAST IMAGING AGENTS PREFILLED SYRINGES) 267
9 PREFILLED SYRINGES GLOBAL MARKET, BASED ON USABILITY 274
9.1 INTRODUCTION 274
9.2 DISPOSABLE PREFILLED SYRINGES 277
9.3 REUSABLE PREFILLED SYRINGES 286
10 PREFILLED SYRINGES GLOBAL MARKET, BASED ON MOLECULE TYPE 289
10.1 INTRODUCTION 289
10.2 LARGE MOLECULE PREFILLED SYRINGES 291
10.3 SMALL MOLECULE PREFILLED SYRINGES 300
11 PREFILLED SYRINGES GLOBAL MARKET BASED ON ROUTE OF ADMINISTRATION 306
11.1 INTRODUCTION 306
11.2 SUBCUTANEOUS PREFILLED SYRINGES 309
11.3 INTRAMUSCULAR PREFILLED SYRINGES 318
11.4 INTRAVENOUS PREFILLED SYRINGES 322
11.5 OTHER ROUTES PREFILLED SYRINGES (INTRA-ARTICULAR PREFILLED SYRINGES, TOPICAL PREFILLED SYRINGES, INTRA-VITREAL PREFILLED SYRINGES) 326
12 REGIONAL ANALYSIS 333
12.1 INTRODUCTION 333
12.2 NORTH AMERICA 338
12.2.1 U.S. 361
12.2.2 REST OF NORTH AMERICA 374
12.3 EUROPE 386
12.3.1 GERMANY 410
12.3.2 ITALY 422
12.3.3 FRANCE 433
12.3.4 REST OF EUROPE 443
12.4 ASIA-PACIFIC 454
12.4.1 CHINA 480
12.4.2 JAPAN 491
12.4.3 INDIA 502
12.4.4 REST OF APAC 513
12.5 REST OF THE WORLD 525
12.5.1 BRAZIL 551
12.5.2 REST OF LATIN AMERICA (LATAM) 561
12.5.3 MIDDLE EAST AND AFRICA (MEA) 572
13 COMPETITIVE LANDSCAPE 583
13.1 INTRODUCTION 583
13.2 PRODUCT LAUNCH 585
13.3 EXPANSION 588
13.4 COLLABORATION 590
13.5 INVESTMENT 592
13.6 OTHER DEVELOPMENTS 593
14 MAJOR COMPANIES 596
14.1 BECTON, DICKINSON AND COMPANY 596
14.1.1 OVERVIEW 596
14.1.2 FINANCIALS 597
14.1.3 PRODUCT PORTFOLIO 601
14.1.4 KEY DEVELOPMENTS 602
14.1.5 BUSINESS STRATEGY 603
14.1.6 SWOT ANALYSIS 605
14.2 ELCAM MEDICAL 606
14.2.1 OVERVIEW 606
14.2.2 FINANCIALS 606
14.2.3 PRODUCT PORTFOLIO 606
14.2.4 KEY DEVELOPMENTS 607
14.2.5 BUSINESS STRATEGY 608
14.2.6 SWOT ANALYSIS 609
14.3 GERRESHEIMER AG 610
14.3.1 OVERVIEW 610
14.3.2 FINANCIALS 611
14.3.3 PRODUCT PORTFOLIO 613
14.3.4 KEY DEVELOPMENTS 614
14.3.5 BUSINESS STRATEGY 615
14.3.6 SWOT ANALYSIS 616
14.4 NIPRO CORPORATION 617
14.4.1 OVERVIEW 617
14.4.2 FINANCIALS 618
14.4.3 PRODUCT PORTFOLIO 620
14.4.4 KEY DEVELOPMENTS 621
14.4.5 BUSINESS STRATEGY 621
14.4.6 SWOT ANALYSIS 623
14.5 OWEN MUMFORD LTD 624
14.5.1 OVERVIEW 624
14.5.2 FINANCIALS 624
14.5.3 PRODUCT PORTFOLIO 624
14.5.4 KEY DEVELOPMENTS 625
14.5.5 BUSINESS STRATEGY 626
14.5.6 SWOT ANALYSIS 628
14.6 SCHOTT AG 629
14.6.1 OVERVIEW 629
14.6.2 FINANCIALS 630
14.6.3 PRODUCT PORTFOLIO 632
14.6.4 KEY DEVELOPMENTS 633
14.6.5 BUSINESS STRATEGY 634
14.6.6 SWOT ANALYSIS 635
14.7 SHANDONG WEIGAO GROUP MEDICAL POLYMER COMPANY LIMITED 636
14.7.1 OVERVIEW 636
14.7.2 FINANCIALS 637
14.7.3 PRODUCT PORTFOLIO 640
14.7.4 KEY DEVELOPMENTS 640
14.7.5 BUSINESS STRATEGY 641
14.7.6 SWOT ANALYSIS 642
14.8 STEVANATO GROUP S.P.A. 643
14.8.1 OVERVIEW 643
14.8.2 FINANCIALS 644
14.8.3 PRODUCT PORTFOLIO 647
14.8.4 KEY DEVELOPMENTS 647
14.8.5 BUSINESS STRATEGY 648
14.8.6 SWOT ANALYSIS 650
14.9 TERUMO CORPORATION 651
14.9.1 OVERVIEW 651
14.9.2 FINANCIALS 652
14.9.3 PRODUCT PORTFOLIO 655
14.9.4 KEY DEVELOPMENTS 655
14.9.5 BUSINESS STRATEGY 656
14.9.6 SWOT ANALYSIS 657
14.10 YPSOMED HOLDING AG 658
14.10.1 OVERVIEW 658
14.10.2 FINANCIALS 659
14.10.3 PRODUCT PORTFOLIO 661
14.10.4 KEY DEVELOPMENTS 661
14.10.5 BUSINESS STRATEGY 662
14.10.6 SWOT ANALYSIS 663