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3D Cell Culture Global Market – The Next Element of Progress

Posted in Biotechnology by Adolf on Apr 27,2022 355

Advances in science have made it possible for us to think even the unimaginable coming to life. Emerging technologies are not only bringing new innovations in the healthcare sector, but is also providing solutions to critical clinical issues. Cell biology, genetics, molecular biology, cell culture, biomedical technologies etc. are just some of the trending improvements in the life science market.

While we are on the topic about 3D cell culture, let us seek more details on the subject. Cell culture is an indispensable in-vitro tool used to understand the cell biology, the tissue morphology, mechanisms of diseases and drug action. We are already aware about the 3D technology, which is used to give visual information in a dynamic setting and now the same expertise has gained interest in various applications of science.

A 3D cell culture is an artificially-created environment in which biological cells are permitted to grow or interact with their surroundings in all three dimensions. Unlike 2D environments (e.g. a petri dish), a 3D cell culture allows cells in vitro to grow in all directions, similar to how they would in vivo. These three-dimensional cultures are usually grown in bioreactors, small capsules in which the cells can grow into spheroids, or 3D cell colonies. Approximately 300 spheroids are usually cultured per bioreactor.

The 3D cell culture technologies are emerging as an important tool over the conventional 2D cell culture system, which can facilitate research in the biomedical field with more realistic results. 3D cell culture models such as organoids, spheroids are showing great potential in many applications including basic research, cancer research, stem cell research, drug discovery & toxicity screening and regenerative medicine to better understand complex biology in a physiologically relevant context where 2D models have not proven as successful. Further development of advanced 3D cell culture products or technologies, and emerging high potential bioprinting technologies will further expand the 3D cell culture applications areas and increase their adoption.

The 3D Cell Culture Global Market is expected to grow at a mid-teen CAGR from 2021 to 2028 to reach US$2,867.1 million by 2028. The factors such as increasing funding towards the cell based research, increasing focus towards the application 3D cell culture models in in-vitro testing in drug discovery, toxicity testing due to advantages over 2D cell culture system are driving the 3D cell culture market. Whereas, growing focus towards application of 3D cell culture in the personalized and regenerative medicine and advancement is 3D cell culture technologies will provide immense growth opportunities for the 3D cell culture market.

The market for 3D cell culture is segmented based on technology, products, end-user and geography. Based on the technology, the market is segmented into scaffold based platforms, scaffold free platforms and bioprinting. Among technologies, Scaffold based platforms is accounted for the highest revenue in 2021 and is expected to grow at a low teen CAGR from 2021 to 2028. Scaffold free platforms are expected to grow at a mid-teen CAGR from 2021 to 2028. The scaffold based platforms is further segmented into solid scaffolds, hydrogels and others. Among these, Solid Scaffolds segment is accounted for the highest revenue in 2021 and is expected to grow at a low teen CAGR from 2021 to 2028. Hydrogels is expected to grow at a mid-teen CAGR from 2021 to 2028. The scaffold free platforms is further sub-segmented into hanging drop method, agitation based method, forced floating and microfluidics. Among these, Forced floating segment is accounted for the highest revenue in 2021 and is expected to grow at a mid-teen CAGR from 2021 to 2028.

Based on the products, the 3D cell culture market is classified into Cells & tissues, Media, Sera and Reagents, Microplates & Others, assay kits, scaffolds and Instruments. Among the products, media, Sera and Reagents accounted for the highest revenue in 2021 and are expected to grow at a mid-teen CAGR from 2021 to 2028. Based on applications the 3D cell culture market is divided into basic research, toxicity and drug safety screening, tissue engineering, stem cell research, drug discovery, cancer research, and others. Among the applications, cancer research accounted for the highest revenue in 2021 and is expected to grow at a mid-teen CAGR from 2021 to 2028.

Based on end users, 3D cell culture market is segmented into academic and research institutes, biotechnology and pharmaceutical industry, and others. Among these Biotechnology & Pharmaceutical segment is accounted for the highest revenue in 2021 and is expected to grow at a mid-teen CAGR from 2021 to 2028. Other end-user such as CRO’s is also expected to grow due to increasing focus towards the adoption of 3D cell culture model in drug discovery by the CRO’s. By geography, North America accounted for the largest revenue of in 2021 and is expected to grow at a low teen CAGR from 2021 to 2028.

In spite of negative supply chain impact, the market witnessed positive demand in case of COVID-19 research, as 3D cell culture models were effectively employed to study host–virus interactions, and the disease course of COVID-19. Companies are adopting various organic and inorganic strategies to expand their market in a competitive market. To gain market share, companies are constantly focusing on developing innovative technologies and differentiated products.

The key players in the 3D cell culture global market include Thermo Fisher Scientific (U.S.), Corning (U.S.), Lonza (Switzerland), Merck KGaA (Germany), Insphero (Switzerland), Reprocell (Japan), Greiner-Bio (Austria), Mimetas (Netherlands), Aspect Biosystem (Canada), BICO (Sweden) and 3D systems (U.S.).


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